Looking for the best CBD vape pens in the UK? We’ve tried and tested over 150 CBD brands on the market and have listed the 10 best CBD vape pens of 2021.
CBD Vapes UK: The 10 Best CBD Vape Pens in 2021
CBD products have been growing in popularity over the last few years, due to its range of health applications – including pain relief, alleviating insomnia, lowering stress levels, reducing anxiety and depression, fighting the side effects of cancer medications, improving acne outbreaks, counteracting heart disease, or reducing seizures in patients with epilepsy.
Sales of CBD vape pens in particular have skyrocketed as vaping is a popular way to get your daily dose of CBD as inhalation is an efficient way to consume CBD because it bypasses the digestive tract and liver allowing CBD to be readily absorbed.
It’s also fast-acting and provides relief within 10-20 minutes.
Yet with over 150 CBD brands on the market, it can be difficult to choose the right CBD vape pen to match your personal needs. This is why the CBD Unboxed team has tried and tested most CBD products and brands available in the UK market and assessed them across 7 key areas:
- Value for Money
- Product Range
- Customer Reviews
- Lab Testing
- Shipping & Delivery
Based on our findings, we have hand-picked the 10 best CBD vape pens available in the UK in 2021.
Take our CBD Quiz
If after reading this guide you are still unsure about what CBD vape pen to choose, simply take our CBD Quiz which has been designed specifically to identify the product and strength that is best suited to your personal needs.
By testing over 150 different CBD brands and assessing their efficacy, taste, value for money and more, we’ve been able to hand-pick the 10 best CBD vape pens of 2021.
What is CBD?
Cannabidiol — also known as CBD — is one of the multiple chemical compounds found in hemp (cannabis sativa) or marijuana plants. It is also known as medical cannabis, which is a broad term used to encompass any product, treatment, or medicine that includes cannabis-derived ingredients.
It is not however, the same as tetrahydrocannabinol (THC) found in marijuana and contains none of the psychoactive properties associated with it, which means CBD won’t get you “high”.
So What’s the Difference?
Different parts of the cannabis plant are either defined as hemp or as cannabis and marijuana.
- Hemp: hemp is the stalks, stems and sterilized seeds of cannabis sativa (“Cannabis Sativa” is the scientific Latin term that defines hemp, cannabis or marijuana plant species).
- Cannabis and Marijuana: the leaves, flowers and viable seeds of cannabis sativa.
The varieties of cannabis that are regulated, legal and available in the UK are those that produce less than 0.2 percent THC. And given the fact that most THC is in the flowers, CBD products are primarily made from hemp (stalks, stems and sterilized seeds of cannabis sativa) which contain very little THC and are safe to consume.
This is why CBD products are legal in the UK if they contain less than 0.2% THC.
Therapeutic Properties of CBD
There has been a lot of interest in CBD from both the research and medical community over the last few years, due to its range of health applications – including but not limited to pain relief, fighting the side effects of cancer medications, alleviating insomnia, lowering stress levels, improving acne outbreaks, counteracting heart disease, or reducing seizures in patients with epilepsy
Products containing CBD come in many different forms, with the most common including CBD oils, CBD gummies, CBD capsules, CBD drinks, CBD vapes and a range of CBD edibles. Some forms are more fast-acting than others, some have different flavours, some contain differing proportions of CBD extract, and so on, so the type you choose depends entirely upon your personal preferences and the condition you wish to treat.
What are CBD Vape Pens & e-Liquids?
CBD Oil vs CBD Vape Oil
Whilst CBD vape or vape pens are commonly referred as using CBD oil, it is important to note that the CBD oil used for vaping is different from traditional CBD oil (also called CBD tinctures).
This can be quite confusing for people who have never used CBD products before as CBD tinctures and CBD used for vaping or inhaling are both referred to as ‘CBD oil’. The best way to not get mixed-up is to differentiate them by calling CBD tinctures (which are ingested) “CBD oil” and by calling vaping products either “CBD vape oil”, “CBD vape juice” or “CBD distillate”.
CBD tinctures are strictly for ingestion purpose and should not be used for inhalation or vaping as these products were not designed to be exposed to high heats for vaporisation, unlike CBD vape juices and e-liquids.
CBD vape oil is made using a similar process to standard CBD oil in that it is derived from the hemp plant and use CBD extract. However, unlike CBD oil which use MCT or Olive oil as a carrier, CBD vape juices use thinning agents such as Vegetable Glycerin (known as VG), a thick, sweet liquid or Propylene Glycol (known as PG), a much thinner and tasteless liquid. It is the presence of these thinning agents that make the CBD juice ok to vape or inhale.
Products using Propylene Glycol tend to produce more of a “throat hit” than Vegetable Glycerin does, and as a result may simulate the feel of smoking better.
So what are the different types of CBD vape pens available in the UK and which one should you pick? You will essentially have the option between:
- Disposable CBD vape pens
- Refillable CBD vape pens
- Refillable CBD vapes
- Refillable CBD vape pods (e.g. JUUL e-cigarettes)
Disposable CBD Vape Pens
As the name indicates, these CBD vape pens are small cigarette style pens which have been pre-filled with CBD vape oil and are disposable, meaning you will not be able to refill them. They work thanks to a built-in coil and battery. When the person smoking sucks on the mouthpiece of the vape pen, the battery sends a charge to the coil which causes the temperature to rise in the atomizer. This process heats-up the CBD vape oil in the cartridge and transforms it into vapor which can then be inhaled.
CBD vape pens are a great way to start as you do not need to worry about how they work or refilling them. Simply turn them on and start vaping. However, their longevity is usually limited to 100-150 large inhalations which is not idea if you are a heavier CBD smoker.
Some of the best CBD vape pens include:
|CBDfx – Terpenes Vape Pen||50mg||£12.99|
|CBDfx – CBD Vape Pen||30mg||£9.90|
|Vaay – CBD Vape Pen||250mg||£34.90|
Refillable CBD Vape Pens
Refillable CBD vape pens are exactly the same as disposable ones, the main difference being that small cartridges filled with vape oil can be purchase separately in order to replace empty cartridges.
These vape pens are usually a little more expensive as you are essentially buying a vape pen that you will keep for a long time, instead of something that’s disposable. Unlike big CBD vapes (see below), CBD vape pens tend to be small and quite discreet, so they’re the ideal companion when you’re on the go.
CBD vape pens are used with compatible CBD oil cartridges. The cartridges come pre-filled with CBD vape oil or CBD distillate (more on this below) and hold between 0.5ml and 1ml of CBD vape juice. You will need to be sure that the CBD oil cartridges you bought are compatible with the CBD vape pen you already possess since vape pens come in different shapes and sizes.
For instance, the Provacan CBD Vapepod can only be refilled with the compatible Terpenes CBD vapepods from Provacan. Be sure to check what pre-filled cartridges are available from the brand before buying a refillable vape pen as this may limit your CBD smoking experience.
A couple of good refillable CBD vape pens options include:
|Provacan – CBD Vapepod||360mg||£99.99|
|Vsavi – CBD Vape Kit||300mg||£42.95|
Refillable CBD Vapes
These work exactly in the same way as refillable CBD vape pens but are rechargeable using CBD vape oil instead of pre-filled cartridges, so you can fill it up with your own CBD vape juice.
It is worth noting that refillable CBD vape pens often produce more smoke, vapor and flavour than disposable ones as the built quality is better. Whilst they may require some basic maintenance such as changing the coil or cleaning the tank, they tend to be more cost-effective in the long run. However, they may not be as versatile as CBD pods since the oil inside the cartridge cannot be swapped for nicotine one without having to dispose of the CBD vape oil first.
A good option is the CBDfx Vape oil Kit:
|CBDfx – CBD Vape Oil Kit||1ml||£29.99|
|Xeo Void – CBD Vaporizer||2ml||£39.99|
JUUL e-cigarettes have become incredibly popular and use their own proprietary technology and vape pods. Their e-cigarettes look like small USB keys which can be recharged in an hour via USB port. They are a modern take on e-cigarettes and as such do not use traditional vape oil but small vape pods which are simply inserted into the e-cigarette.
Users can switch between standard nicotine pods (different strengths available) and compatible JULL CBD pods in an instant, making it the ideal solution for those who want to consume both nicotine and CBD without the hassle of having to carry two vape pens or having to refill them.
As with CBD oil cartridges, be sure to choose a product that is compatible with your e-cigarette. Whilst a lot of pods look the same as JUUL pods, be aware that they may not be compatible.
The 10 Best CBD Vape Pens of 2021
- V2 PRO 7 CBD vaporiser pen (choose from Black, Stainless Steel and Blue)
- Magnetic USB charging lead
- Wall adapter (UK or EU)
- Magnetic CBD E-Liquid Cartridge
- Magnetic Loose Leaf Cartridge
- Pick and brush used for Loose Leaf Cartridge maintenance
Vapour2 Pro CBD
Vapour2 PRO Series 7 CBD Vaporizer
Different Types of CBD
Before buying one of the 10 best CBD vape pens recommended above, it is important to understand the different types of CBD available in the market. These fall under three main categories:
- Full-Spectrum CBD: CBD products labelled as “full-spectrum” contain all the phytochemicals that occur naturally in the cannabis plant, including other cannabinoids, terpenes, and oils. It also contains some trace amounts of THC (tetrahydrocannabinol), the psychoactive compound in marijuana that produces the “high” effect. However, the total amount of THC for the UK market is limited to 0.2% so full-spectrum CBD gummies will provide all the benefits of CBD without the “high”.
- Broad-Spectrum CBD: CBD products labelled as “broad-spectrum” contain all the phytochemicals that are in the cannabis plant but does not contain any THC.
- CBD Isolate: CBD products labelled as “isolate” is the pure form of CBD and contain no other cannabis plant compounds such as other cannabinoids, terpenes, and oils. CBD isolate is a good option for those who want to take CBD gummies, but who do not want to benefit from the “entourage effect” of other plant compounds or ingest any tetrahydrocannabinol (THC), which are present in full and broad spectrum products.
What is the ‘Entourage Effect’?
Now that you know how CBD works and what the 10 best CBD vape pens in the UK are, it is important to understand the concept of ‘entourage effect’ to ensure that you select the CBD product that is best suited to your personal circumstances.
The entourage effect is the theory that while each botanical compound has a unique role or benefit, its behaviour may change when the presence of another compound is present.
For example, it would be more effective and quicker to produce a play with a team of actors rather than one actor playing all the parts. When each actor has a specific role to focus on, they can learn their lines and direction and support their fellow actors. But one actor alone will take a lot longer to learn all the lines for the various parts they have to play.
This is similar to the entourage effect. Essentially, everyone knows their role, but their performance can be enhanced by comradery.
But how is this applied to CBD?
We know that CBD products stimulate the endocannabinoid system and make it work more efficiently. But different CBD products affect the ECS differently, depending on their formulation. As previously, discussed there are 3 types of CBD formulation:
- Full-spectrum: No additional extraction, contains all the natural ingredients of the hemp plant, including CBD, THC, terpenes and flavonoids.
- Broad-spectrum: All traces of THC are removed from the oil. Every other ingredient remains.
- CBD Isolate: The oil only contains CBD, everything else is removed.
One of the above formulations has been proven to give better results in reducing pain, inflammation and many other symptoms. Which one of these formulations do you think stimulates the ECS best?
Would it be the most natural substance (full-spectrum), the one with any psychoactive ingredients (broad-spectrum) or the purest form of CBD (isolate)?
According to the entourage effect, it is the full-spectrum CBD because it keeps all the natural components of the hemp plant, which include:
Cannabinoids and Terpenes
The theory of the entourage effect was first introduced by Dr Ethan B. Russo. He thinks that cannabinoids such as CBD and THC work with terpenes (aromatic component) to produce a “synergy.”
In his study “Taming THC: Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects” (2010) Dr Ethan B Russo suggests:
- The terpene pinene, which gives the scent of pine, may help counteract compromised memory caused by THC.
- CBD and terpene limonene, which gives a citrus scent, might work together to alleviate anxiety.
- A combination of CBD and terpene caryophyllene, offering a pepper smell, may be beneficial in the treatment of addiction.
The possibility of “synergy” of endless but have not yet been categorically proven. For more information read his other study “The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain, No Gain” published in 2019.
Omega-3, Antioxidants and Nutrients
In addition to CBD, THC and terpenes, full-spectrum CBD oil also contains Omega-3, which is vital to the ECS. Omega-3 is used to maintain the receptor CB1, which regulate pain and memory.
It also aids the absorption of external cannabinoids, as well as making endocannabinoids internally.
Other nutrients and antioxidants have also been discovered in full-spectrum CBD oil, for example, Vitamin E. Vitamin E is a fat-soluble compound that can prevent cataract formation, postpone the appearance of wrinkles and grey hair, boosts the immune system and reduces inflammation.
As you can see CBD, when first extracted from the hemp plant has a huge list of ingredients. All of them seem to play a part in helping our bodies. We may not know exactly what they all do. But as time passes and research continues, we can learn more.
What Type of CBD is Best?
There’s not really a best type of CBD. It all depends on your personal circumstances. Below are some of the pros and cons of using isolate vs full-spectrum CBD products.
Full-spectrum CBD is ideal for those who want to:
- Benefit from all of the naturally occurring cannabinoids, terpenes, and flavonoids found in hemp
- Benefit from the entourage effect
- Ingest THC – albeit in small doses
CBD isolate is ideal for those who need to:
- Take larger doses of CBD as they will not increase their THC consumption
- Take regular drug tests and who may worry about THC showing up on their results. This is especially the case for people working in the armed forces, athletes or people working in banking / trading.
CBD Isolate: Best for Vaping
Whilst there are added benefits of using full and broad-spectrum products, It is worth noting that very few studies cover the suitability of whole plant CBD for vaping or inhaling.
A number of manufacturers have conducted their own toxicological assessments and have deemed whole plant hemp extract & full spectrum CBD oil unsuitable for use in the formulation of CBD e-liquid.
For this reason, the vast majority of CBD vape liquids on the market have been formulated using only CBD isolate.
Advantages of CBD Vape Pens
Easy to Use & Discreet – Whether you are vaping using traditional vaping juices or CBD infused e-liquids, most people will not be able to tell the difference especially since many e-liquids come in various flavours.
Increased Bioavailability – Inhalation is an efficient way to consume CBD because it bypasses the digestive tract and liver allowing CBD to be readily absorbed through the thin membranes that line the air sacs of the lungs (alveoli) where it enters directly into the bloodstream.
Fast Acting – Due to its increased bioavailability, CBD vaping will usually act much faster than other products that needs to go through the digestive tract.
Great Tasting – Whilst traditional CBD oil will usually have an earthy or grassy taste, CBD vaping juices will usually be flavoured with agents such as raspberry, lemon, strawberry, peach or blackcurrant making it a great tasting alternative to oils which tend to leave an unpleasant aftertaste in your mouth.
No Addictive or Withdrawal Issues – Finally, CBD drinks are a natural remedy that can be taken by almost anyone and possesses none of the addictive or withdrawal issues that other pain management or anxiety medications may present.
Disadvantages of CBD Vapes
Whilst there are quite a few advantages to getting your daily dose of CBD using CBD e-liquids, there are unfortunately several drawbacks which are worth considering.
Lack of Research – as highlighted in a previous section, most research papers have focused on the efficacy of traditional CBD tinctures. However, there is little evidence that from the research and medical community that establishing the health benefits of vaping.
Thinning Agents – A major risk linked to CBD vape pens is thinning agents. Since CBD extract is usually too thick to be used for vaping products, manufacturers use a thinning agent – such as propylene glycol and polyethylene glycol. The downside of thinning agents is that when heated to high temperatures, as is the case with a vape pen, they can break down into potential carcinogenic compounds (resulting in cancer) and may cause respiratory complications.
Addiction – Whilst CBD does not have addictive properties, the process of CBD vaping by itself has been found to be addictive by a few studies. The risk of such addiction is simply that your consumption of CBD may increase, especially if you are not tracking your CBD intake closely.
Interaction with other medications – It’s also worth noting that CBD may make it harder for your body to process certain medications, so if you are taking any other medications, be sure to check with your GP before taking CBD products.
Minor side effects – Finally, CBD can cause side effects in some people including drowsiness, changes in mood, nausea, and changes in appetite. Every individual will be affected differently, and in most cases, there are no side effects to worry about.
Therapeutic Properties of CBD
CBD vape pens and e-liquids – along with other CBD products – possess a number of therapeutic properties that are backed by various scientific research papers and double-blind studies.
Although there are very few research papers on vaping and e-liquids, some of the most discussed health benefits of CBD amongst the public and the medical community include.
Pain Relief (Analgesic Properties)
CBD has Analgesic properties, meaning that it helps relieve pain. But how?
The human body contains a specialized system called the ECS (the endocannabinoid system), which aim is to regulate a variety of functions such as sleep, appetite, pain and immune system response. The body also produces endocannabinoids, which are simply neurotransmitters that bind to cannabinoid receptors in your nervous system.
CBD is believed to interact with specific receptors, specifically the CB1R and CB2R.
- CB1 receptors, which are located in various regions of the body, with a large concentration in the central nervous system and brain, co-ordinate mood, emotion, appetite, and other functions.
- CB2 receptors are more commonly found in the immune system and are responsible for controlling inflammation and pain. CBD stimulates these receptors and induces the body to release serotonin.
Serotonin, or 5-HT, is a neurotransmitter that carries signals from one neuron to the other. CBD increases the level of serotonin, which, in return, helps reduce pain, reduce inflammation in the body and possibly reduces the cramping experienced during period pain.
According to Researchgate, a study published in November 2019 shows improvement of physical discomforts such as headaches and various signs of physical pain. According to Teitelbaum J, there have been multiple studies showing patients found relief of menstrual pain, back pain, spinal pain, joint pain (e.g. arthritis) or fibromyalgia pain.
Reduce Anxiety & Depression
CBD has been proven to reduce the symptoms of anxiety and depression. Some of the more commonly diagnosed anxiety disorders that CBD can help with include:
- Generalised anxiety disorder – also known as GAD
- Obsessive-compulsive disorder – also known as OCD
- Social anxiety disorder – also known as social phobia or SAD
- Panic disorder
- Post-traumatic stress disorder – Also known as PTSD
- Health anxiety – people experiencing obsessions and compulsions relating to illness
- Body dysmorphic disorder – Also known as BDD
- Perinatal anxiety – Also known as perinatal OCD
Most people who suffer from anxiety will experience a hyper-active amygdala, a collection of cells near the base of the brain.
CBD helps to ease the symptoms of anxiety by regulating the functions of the amygdala and the hippocampus and therefore their effects on how our brain processes potentially anxiety ridden situations. But how?
CBD has been proven to increase cerebral blood flow to areas of the brain associated with memory processing, specifically the hippocampus. The findings identify a potential mechanism for the use of CBD to treat disorders associated with altered memory processing, including Alzheimer’s disease, PTSD, and schizophrenia.
Put it simply, a single dose of cannabidiol (CBD) helped increase blood flow to the hippocampus, an important area of the brain associated with memory and emotion, which means that CBD has been proven by several scientists and medical professionals to help smooth the cognitive processes of this part of the brain.
According to Dr Michael Bloomfield from UCL: “Cannabidiol is one of the main constituents of cannabis and is gaining interest for its therapeutic potential. There is evidence that CBD may help reduce symptoms of psychosis and anxiety as well as improve memory function. Additionally, CBD changes how the brain processes emotional memories, which could help to explain its reputed therapeutic effects in PTSD and other psychiatric disorders.”
These finding have been backed by double blind studies where on different occasions, separated by at least a week, each participant was given a 600mg of oral CBD or a placebo. The doses came in identical capsules, so participants did not know which one they were taking on which occasion (https://neurosciencenews.com/cbd-hippocampus-16806/)
Researchers measured blood flow to the hippocampus using ‘arterial spin labelling’ – an MRI (magnetic resonance imaging) brain scanning technique which measures changes in the blood oxygen levels.
In another double-blind study in Brazil, 57 participants received either CBD oil or a placebo 90 minutes before they underwent a simulated public speaking event. The researchers found that a 300-mg dose of CBD was the most effective at significantly reducing anxiety during the event.
Reduce Side Effects of Cancer Treatments
CBD has been proven to have antiemetic properties, meaning it helps prevent vomiting.
This discovery has been particularly useful for cancer patients for whom CBD has been proven to not only help them reduce the symptoms and side effects of cancer and cancer medication, such as pain, nausea and vomiting.
In one study focusing on CBD extract and THC extract given to patients with intractable cancer-related pain, it was found that of the 177 people with cancer-related pain who did not experience the adequate relief from traditional pain medication, those treated with an extract containing both the CBD and THC compounds experienced a significant reduction in pain compared to those who received only THC extract. This would therefore suggest that CBD had a net positive effect when it comes to reducing pain in cancer patients.
A separate study also showed that cancer patients who suffered from the various side effects of chemotherapy – including nausea and vomiting – experienced little relief from traditional anti-emetic treatments. Patients suffering from chemotherapy-induced nausea and vomiting (CINV) were administered a one-to-one combination of CBD and THC via mouth spray. The results showed that chemotherapy-related nausea and vomiting symptoms were reduced in comparison to standard treatment alone.
Help with Arthritis
CBD has been proven to have antiarthritic properties, meaning that it helps relieve or prevent arthritic symptoms.
The two most common types of arthritis are:
- Rheumatoid arthritis is an autoimmune condition wherein a person’s immune system attacks their joints, causing inflammation. It commonly affects the hands and feet and leads to painful, swollen, and stiff joints.
- Osteoarthritis is a degenerative condition that affects joint cartilage and bones, causing pain and stiffness. It often affects the hip, knee, and thumb joints.
According to a poll conducted by the Arthritis Foundation, 29% of 2,600 patients with either osteoarthritis (52%) or rheumatoid arthritis (45%) for 10 or more years, stated using CBD in liquid or topical form to manage their arthritis symptoms, especially pain.
Of those using CBD, most reported improvement in physical function, sleep, and well-being:
- 67% reported improvement in their physical function
- Over 30% said it provided relief from morning stiffness and helped them to get moving
- 71% reported improvements in their ability to sleep
- Over 30% said it helped relieve symptoms of fatigue
But CBD also helped those suffering from arthritis improve their overall well-being, with people who used CBD reporting emotional and mental health benefits, in addition to relief of physical pain.
- 41% reported a better overall sense of well-being
- 77% reported a lower level of anxiety
- 67% reported effectiveness in improving depressed mood
From a research standpoint, while there are various studies suggesting CBD might be a promising approach, and animal studies showing anti-inflammatory and pain-relieving effects, well-designed studies demonstrating compelling evidence that CBD is effective for chronic arthritis pain in humans do not yet exist.
Help With Neurological Disorders & Epilepsy
CBD appears to have neuroprotective properties, meaning that it helps protect nerve cells against damage, degeneration, or impairment of function.
This is particularly interesting for patients suffering from neurological disorders such as multiple sclerosis, epilepsy or children with Dravet syndrome.
Researchers believe that CBD can act on the ECS (the endocannabinoid system) as well as other brain signalling systems to provide benefits to those patients and early studies show promising results.
When it comes to MS (multiple sclerosis), an oral spray called Sativex and consisting of CBD and THC has been proven to be an effective way to reduce muscle spasticity (muscle spasms) in patients. The study found that Sativex reduced spasms in 75% of patients with MS who were experiencing muscle spasticity and for which traditional medications were not working.
As for Epilepsy, CBD appears to have anticonvulsant properties, meaning that it helps prevent or reduce the severity of epileptic fits or other convulsions. What is the research behind this?
According to the Epilepsy Society, medical cannabis – a medicine that contains cannabis, cannabis resin, cannabinol or a cannabinol derivative and that is produced for medicinal use in humans – has been proven to reduce the number of seizures in patients suffering from epilepsy.
Three separate double-blind randomised controlled trials of pure CBD (CBD isolate) in children and young people with epilepsy have shown a reduction in the number of monthly seizures experienced by patients compared to those that received placebos. Additional studies have shown that it may also have an anti-epileptic effect in the epilepsies in general, not just in children and young adults.
Improve Heart Health
CBD appears to have anti-inflammatory properties, meaning that it helps reduce inflammation (redness, swelling, and pain) in the body.
But what is inflammation? Inflammation is a natural process occurring in your body whereby your white blood cells and what they produce, protect you from infection from bacteria and viruses.
However, in some people, their own body’s defence system (i.e. their immune system) is deregulated and triggers inflammation when there are no infection from bacteria or viruses to fight off. Called autoimmune diseases, they attack healthy tissues as if they were infected, causing damage to these tissues in the process.
Inflammation can either be acute (i.e. short-lived) and go away within a few hours or days, or chronic (i.e. long-lasting) and last for months or years.
Inflammation is known to lead to many heart related diseases, including coronary heart disease, high blood pressure and stroke. Inflammation of the heart (myocarditis) may cause shortness of breath or fluid buildup, inflammation of the small tubes that take air to your lungs may cause shortness of breath and inflammation of the kidneys (nephritis) may cause high blood pressure or kidney failure.
There is some evidence that CBD has anti-inflammatory properties and that it may be beneficial to the cardiovascular system, with CBD having direct actions on isolated arteries, causing both acute and time-dependent vasorelaxation (reduction of vascular tension).
According to existing studies, CBD protects against the vascular damage caused by a high glucose consumption (sugar), inflammation or the induction of type 2 diabetes in animals. It has also been proven to reduce the vascular hyperpermeability associated with such environments. Vascular hyperpermeability is the excessive leakage of fluid and proteins from blood vessels to the interstitial space which often leads to multiple organ failure resulting in patient death.
A common theme throughout these studies is the anti-inflammatory and anti-oxidant effect of CBD. In the heart, in vivo CBD treatment protects against cardiomyopathy associated with diabetes.
Other studies have shown that CBD can have a protective effect on the heart. This was the case with one study showing the benefits of CBD in rats after a heart attack and in mice with heart damage associated with diabetes.
Studies also indicate that CBD may be beneficial for patients with high blood pressure.
One study of nine healthy men, who were given one dose of 600 mg of CBD oil, found that it reduced resting blood pressure, compared to patients who had received a placebo. The same study got the patients to go through a stress test to assess the impact of the test on their blood pressure. It found that patients who had received a single dose of 600 mg of CBD experienced a smaller blood pressure increase in comparison to those who had received the placebo.
This would suggest that CBD reduces the stress and anxiety of patients, ultimately leading to a lower blood pressure, even when put under a stressful situation.
Improve Your Sleep
Whilst the Mayo Clinic emphasies that most adults need seven to eight hours a night, nearly 23 per cent of people living in the UK only sleep between five and six hours at night. That’s an estimated 34.5 minutes less than the rest of the world.
Various conditions prevent people from getting a good night’s rest.
- Insomnia – Studies in the UK show 31 per cent of adults have insomnia. Many consumers take CBD to reduce anxiety and high-stress levels. Anxious and racing thoughts are the leading cause of insomnia. Dr Herve Damas, an endocannabinoid expert, explains to Prevention Magazine, “CBD has been shown to have anxiety-relieving effects, and anxiety disorders can be a cause of insomnia.”
- Circadian rhythm disorders – Fewer citizens in the UK have circadian rhythm disorders. Research is available about the potential benefits of CBD for CRD. As mentioned, the ECS helps regulate sleep cycles. The few participants in studies saw improved sleep with cannabidiol.
- Restless legs syndrome – The few reports available show CBD may help consumers losing sleep to movement disorders. Medical researchers don’t know much about the cause of the condition. Many patients need narcotics to reduce the movements, which aren’t safe for long-term use.
- Idiopathic hypersomnia – The uncommon disorder is dangerous because it leaves suffers groggy and sleepy nearly all the time. One study proposes that in the right doses, CBD can act as a wake-promoting agent.
- Parasomnias – Another rare condition that causes people to complete tasks in their sleep, taking away from their rest, and putting them in potentially dangerous situations. Experts have been studying CBD and NREM sleep disorders for a few years. A 2014 report reviewed the connections between NREM sleep disorders, nocturnal seizures, and CBD. Researchers already know the value of CBD as a treatment for seizure disorders.
Most sleep disturbances occur because of stress and anxiety. Calming down the mind is the best way to help people who can’t fall asleep fast or stay asleep get the relief they need.
There is extensive research on the effectiveness of CBD oil when used to treat insomnia and improve sleep.
CBD works with the human body to increase calm, decrease stress, and lower anxiety levels. These responses indirectly improve your sleep. In the 1990s, researchers confirmed the body has an endocannabinoid system or ECS. Researchers have only found a link between the cannabinoids found in hemp with the ECS, making it an unusual reaction.
The ECS is a complex cell-signalling system consisting of endocannabinoids, cannabinoid receptors, and enzymes. Scientists believe it plays many roles, including maintaining balance in the body. When it comes to sleep, the ECS helps regulate sleep and sleep cycles. Also, relating to sleep, a potential function is boosting anandamide to reduce depression and anxiety.
The cannabinoid receptors interact with endocannabinoids and cannabinoids. The CB1 is located in the nervous system and brain. Additionally, the CB2 is found mostly in the immune system and most organs.
A recent surge in scientific publications has found preclinical and clinical evidence documenting value for CBD in some neuropsychiatric disorders, including epilepsy, anxiety, and schizophrenia. Evidence points toward a calming effect for CBD in the central nervous system.
In 2019, a large case series was published in the Permanente Journal about CBD’s calming effects on the central nervous system. The studies showed patients taking CBD saw lower anxiety levels, experienced less stress, and slept better at night. Additionally, most participants experienced no or few side effects.
How Much CBD Should You Consume?
CBD doesn’t have one-size-fits-all dosing and calculating a proper dosage of CBD can be tough as our bodies react to it differently.
Standard CBD Dosage Table
We would first recommend using the above CBD dosage table to determine how much traditional CBD oil (taken under the tongue) you should consume on a daily basis.
The four major factors affecting your CBD dosage are:
- Your weight
- The condition being treated (i.e. depression, chronic pain etc)
- The severity of your condition
- The concentration of CBD oil
Most brands recommend customers start with the lowest dose and increase until they find the right serving size that fits their needs. The most common starting amount is between 10mg and 25mg. For anxiety and depression, the dose can vary from 20mg to 50mg or more.
As a rule of thumb, a person weighting between 10.5 and 17 stones (approximately 150 and 240 lbs) may need between 20mg and 40mg of CBD per day depending on the severity of their symptoms.
CBD e-Liquids Dosage
Now that you know roughly what your CBD intake should be, we can assess how much CBD vape juice you can consume.
Disposable and refillable CBD vapes and CBD pods can be enjoyed in the same way as nicotine smoking using e-cigarettes.
Similar to CBD tinctures, CBD vape juices contain a precise amount of CBD per bottle – usually between 100mg and 800mg of CBD per 10ml bottle – and as such can be much stronger than other CBD products, especially since it has a high absorption rate as it bypasses the digestive system. Be sure to check the strength or your e-liquid and your ideal dosage before vaping it.
When using CBD vapes for the first time, we would always recommend starting with a small dose and working your way up. Most people will start with a 10mg to 25mg of CBD per day to see how their body reacts to it, before increasing the dose by 5mg every 2-5 days if they have not experienced sufficient relief from their conditions or health benefits.
CBD e-Liquid: How Many Drops?
Whilst it may be confusing at the beginning, it’s incredibly simple to work out how many drops of CBD vape oil you need to take depending on your daily requirements and the strength of the product you bought.
Most bottles of CBD e-liquid contain 10ml of product and come in strengths ranging from 100mg to 800mg – also known as 1% and 8% CBD liquids. This simply means that in a 1ml drop of the 100mg bottle, you will have 10mg of CBD, whilst the same 1ml of the 800mg bottle will give you 80mg of CBD.
Assuming you are using the 100mg CBD e-liquid for a daily dose of 20mg, you would need to inhale approximately 2ml of e-liquid per day. If however you bought the 300mg CBD oil, you would only need to take 0.66ml of e-liquid per day to reach the same 20mg target.
|CBD / Bottle||CBD / 1ml||Target*|
*based on 20mg of CBD / day
As with everything, start with a small amount of CBD oil daily to make sure there’s no reaction, then increase slowly by 5mg 3-5 days until finding the right balance.
Is CBD Legal in the UK?
CBD oil, like any other natural remedy, has been used throughout the ages for its medicinal properties. It was evidenced to have been used in ancient societies with the first recorded case in 2727 B.C in China. It was used to treat anything from poor memory and malaria to gout. It has since been used throughout the world to treat various ailments from anxiety to insomnia and menstrual pains.
Throughout the 1940s, there was extensive research into isolating the CBD compound from the other 100+ compounds found within the marijuana plant, due to its lack of psychoactive effects.
It wasn’t until the 1970’s when the US legally recognised the medicinal worth of CBD oil, and it was decriminalised in Oregon. There was a large emphasis on the clear distinction between the CBD compound and the THC compound within the marijuana plant.
The UK followed suit in 2016, making it legal to buy CBD oil to help treat a multitude of health issues, including but not limited to:
- Depression and anxiety disorders (PTSD, OCD, panic disorder or substance/addiction disorders)
- Chronic pain and inflammation
- Heart issues
- Helps to reduce blood pressure and oxidative stress
- Fight bacteria
- Insomnia and sleep related issues
- Helps with symptoms of schizophrenia,
- Skin conditions (psoriasis/eczema)
- Alzheimer’s disease
In a study conducted by the Centre for Medical Cannabis, their results showed that one in six adults in the UK had tried CBD oil, proving that it is one of the fastest-growing, contemporary, well-being products on the market.
Figures also show that the rates of people using CBD oil were higher amongst the under 55 age range. Also, figures were higher amongst females, with 62% of them using CBD to treat anxiety related issues.
Are CBD Vape Pens Fast-Acting?
First-time users may experience relief immediately, as CBD is brand new to your ECS. However, this does depend on the ailment you are trying to improve. For example, one dose of CBD could relieve pain, reduce anxiety and reduce nausea but it wouldn’t stop seizures, cure your depression or diabetes.
If it took you a long time to get the symptom then the same will be said for reducing, preventing or eliminating it.
Immediate Relief (After 24 hours a noticeable difference is seen):
Pain, Inflammation, Migraines, Nausea, Anxiety, Arthritis, Epilepsy, Glaucoma, Stress, Insomnia, Multiple Sclerosis, PTSD, Rheumatism and Motion Sickness.
Short Term Relief (Noticeable between 2-14 days):
Acne, Inflammation, ADD/ADHD, Anxiety, Arthritis, Epilepsy, Depression, Stress, Insomnia, Multiple Sclerosis, PTSD, Rheumatism, Endocrine Disorders, Obesity, OCD, Spinal Cord Injury and Rheumatism.
Long Term Relief (Noticeable between 2+ weeks):
ALS, Addiction, Alzheimer’s Disease, Asthma, Atherosclerosis, Autism, Bipolar Disorder, Cancer, Inflammatory Bowel Disease, Depression, Diabetes, Endocrine Disorders, Fatty Liver Disease, Fibromyalgia, Heart Disease, Huntington´s Disease, Kidney Disease, Metabolic Syndrome, Mood Disorders, Neurodegeneration, Obesity, Parkinson´s Disease, Prion Disease, Schizophrenia and Traumatic Brain Injury.
As you can see from the table above, symptoms which occur quickly can be improved in the same short time frame. Progressive illnesses and their more severe side effects require longer exposure to CBD before a real difference can be seen.
This is just a general guide, literally every single person is different. No one person has the same biology, external factors, ailments and lifestyle.
Side Effects of CBD Vape Pens
Most people do not experience any side effects when taking CBD as this is a natural product. However, as with everything, some people may experience mild side effects from the hemp extract, including:
- Changes in appetite and weight
The best way to decrease adverse reactions is to simply lower your daily intake of CBD, or if taking CBD oil under the tongue, to mix it with your food and drink to mask the taste and reduce potential side effects as the CBD will be processed by the digestive system – which means slower absorption.
How To Choose Quality CBD?
As with anything you ingest or inhale, the source and quality of your CBD products are important. We would always recommend looking at five main aspects before choosing your CBD e-liquid or vape pen.
CBD Vape Juice from Organic Hemp
Hemp can be grown in just the same way as any other plant – mass-produced and using pesticides and GMOs for the greatest profit, or grown organically with care and attention to provide a fantastic end product.
The best CBD is produced from organic hemp that has benefited from plenty of rain during the growing process. While hemp can physically be grown in many countries, it grows best when the temperature is in the low twenties Celsius. Therefore, the location of the hemp farm is important to ensure the optimum environmental factors are accommodated.
And seeing as cannabis plants can be stressed out by the weather, resulting in a higher THC content (above 0.2%), it’s important to ensure that your CBD gummies come from organic hemp which has been grown in the right part of the world.
Less Than 0.2% THC
Cannabis flowers and extracts usually contain two cannabinoids known as THC (tetrahydrocannabinol) and CBD (cannabidiol). Yet the exact percentage of each can vary greatly, depending on the plant variety and the growing technique used.
THC is the main psychoactive compound in cannabis that produces the high sensation, while CBD has been associated with health benefits.
The EU common agricultural policy states that cannabis plant can be grown for industrial uses, provided their THC content does not exceed 0.2 %. That’s in the plant, not in the CBD product you buy.
So when buying CBD vape pens or e-liquid from a shop or online retailer, be sure to check that their products contain less than 0.2% THC.
Clean Extraction Method
Once the hemp is grown and harvested, the CBD needs to be extracted from the plant. There are several methods for doing this, including the use of carbon dioxide (CO2). This produces the cleanest and purest CBD extract but can be expensive to do as the machinery required is not cheap.
Alternative methods include using solvents such as ethanol or plant oils (eg olive oil) to extract the CBD.
This can lead to less-pure CBD extract, as small amounts of solvent or oil can remain, although most companies using this type of extraction method will usually test their CBD extracts to ensure they are solvent free and safe to consume.
Tested by Independent Labs
Another thing we would recommend checking is whether or not your CBD drinks have contaminants. That’s because cannabis plants readily absorb heavy metals, pesticides, and other potentially harmful chemicals that may be in the soil or water.
To ensure your CBD drinks are free of those harmful chemicals, it should be tested frequently while the hemp is growing, and finished products should also be tested, using validated methods.
The extract should be tested and certified by a third-party laboratory to confirm the quality of the CBD. Organic CBD should be GMO-free, pesticide-free, and as pure as possible. In the UK and EU, CBD must register THC content of 0.2% or lower.
Most reputable companies selling CBD vape juice and CBD oil in the UK publish their lab results on their website. Below are a few examples of companies that play the transparency card with their customer and share their lab results for each batch of CBD they produce:
Strength to Match your Needs
Finally, the CBD level within any product should be of a suitable strength to match your needs. Every person is different and their body will respond in a slightly different way, so the level may partially be down to personal preference.
However, higher concentrations might be more suitable for treating different ailments to lower concentrations, and it is wise to check the level of CBD in every product you use.
As a rule of thumb, people looking to use CBD for sleep, anxiety, digestion, relaxation or stress might take between 10mg and 25mg of CBD daily, whilst those using CBD as a pain relief for conditions such as severe arthritis, back pain or migraines may want to use 30mg to 50mg of CBD per day.
Be aware that CBD e-liquids come in different concentration so be sure to track our daily consumption as vaping a 800mg oil instead of a 100mg would increase your CBD intake by 8 fold.
Take the CBD Quiz
If after reading this guide you are still unsure about what CBD vape pen to choose, simply take our CBD Quiz which has been designed specifically to identify the product and strength that is best suited to your personal needs.